Yes, there are several effective ways to prevent or alleviate throat irritation when taking Methylene Blue (MB).

Throat irritation occurs due to MB’s mild acidity, chemical concentration, and direct contact with throat tissues. It's more common with undiluted or improperly ingested doses.

Prevention & Relief Tips

1. Dilute the dose
   
   

• Mix your MB dose (e.g., 0.5–1 mg) in at least 50–100 ml of water

• Stir until fully dissolved for even distribution
  
  

2. Use a Straw
   
   

• Drinking through a straw minimizes contact with throat tissues, reducing irritation
  
  

3. Take After Food
   
   

• MB is gentler when taken after a small meal or a glass of non-acidic milk

• Avoid taking it on an empty stomach.
  
  

4. Citrus Juices may increase irritation
   
   

• Mixing MB with orange, lemon, or acidic drinks, may increase irritation
  
  

5. Chase with Water or Herbal Tea
   
   

• Follow MB intake with a sip of lukewarm water or soothing tea (like chamomile) to wash residue off your throat

Throat irritation from MB is usually minor and avoidable with proper dilution, slower sipping, and post-meal timing. If irritation persists despite precautions, consider switching the form (e.g., capsule) or consulting a healthcare provider.

Note : Taking MB via capsules can bypass the throat lining and may be more comfortable for sensitive users. However, it will reduce the efficacy of MB since sub-lingual absorption is a very good way to make MB effective.